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Preferred Name |
RAD54L RAD54 like
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Definition |
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]
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Synonyms & Abbreviations |
HR54; hHR54; RAD54A; hRAD54
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ReferenceCode |
Location: 1p34.1; Sequence: Chromosome: 1; NC_000001.11 (46247695..46278477)
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ReferenceURL |
https://www.ncbi.nlm.nih.gov/gtr/genes/8438/
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PMID |
NA
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