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Definition |
In patients with biochemical failure after radiation therapy, the biopsy status is a major predictor of outcome,provided the biopsies are obtained 18-24 months after treatment. Given the morbidity of local salvage options,it is thus necessary to obtain histological proof of the local recurrence before treating the patient .TRUS is not reliable in depicting local recurrences after radiation therapy. In contrast, mpMRI has yielded excellent results and can be used for biopsy targeting and guiding local salvage treatment.Detection of recurrent cancer is also feasible with Choline and Acetate PET/CT, but PET/CT has poorer spatial resolution than MRI.
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