Prostate Cancer Ontology
Center for Systems Biology, Soochow University, Suzhou China
PIK3CA
Preferred Name PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Definition Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]
Synonyms & Abbreviations MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; PI3K-alpha; p110-alpha
ReferenceCode Location: 3q26.32; Sequence: Chromosome: 3; NC_000003.12 (179148114..179240093)
ReferenceURL https://www.ncbi.nlm.nih.gov/gtr/genes/5290/
PMID NA
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