Prostate Cancer Ontology
Center for Systems Biology, Sichuan University West China Hospital, Sichuan China
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PHB
Preferred Name PHB prohibitin
Definition This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms & Abbreviations PHB1; HEL-215; HEL-S-54e
ReferenceCode Location: 17q21.33; Sequence: Chromosome: 17; NC_000017.11 (49404048..49414905, complement)
ReferenceURL https://www.ncbi.nlm.nih.gov/gtr/genes/5245/
PMID NA
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