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Definition |
In metastatic CRPC, docetaxel is standard in fit and vulnerable older men, with comparable response and tolerance to younger patients. Tolerability has not been specifically studied in frail older men. In elderly and frail patients, granulocyte colony-stimulating factor prophylaxis should be considered. Cabazitaxel, abiraterone acetate, enzalutamide, and sipuleucel-T increase survival in chemotherapytreated and chemotherapy-naïve senior adults. Palliative treatment includes surgery, radiopharmaceuticals, EBRT, and medical treatment for pain and symptoms.
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