Prostate Cancer Ontology
Center for Systems Biology, Soochow University, Suzhou China
Preferred Name NQO2 N-ribosyldihydronicotinamide:quinone reductase 2
Definition This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Synonyms & Abbreviations QR2; DHQV; DIA6; NMOR2
ReferenceCode Location: 6p25.2; Sequence: Chromosome: 6; NC_000006.12 (2999816..3019876)
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