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Preferred Name |
NQO2 N-ribosyldihydronicotinamide:quinone reductase 2
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Definition |
This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
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Synonyms & Abbreviations |
QR2; DHQV; DIA6; NMOR2
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ReferenceCode |
Location: 6p25.2; Sequence: Chromosome: 6; NC_000006.12 (2999816..3019876)
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ReferenceURL |
https://www.ncbi.nlm.nih.gov/gtr/genes/4835/
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PMID |
NA
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