Prostate Cancer Ontology
Center for Systems Biology, Soochow University, Suzhou China
Preferred Name MAD1L1 mitotic arrest deficient 1 like 1
Definition MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Synonyms & Abbreviations MAD1; PIG9; TP53I9; TXBP181
ReferenceCode Location: 7p22.3; Sequence: Chromosome: 7; NC_000007.14 (1815792..2232971, complement)
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