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Preferred Name |
Flutamide
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Definition |
A toluidine derivative and a nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression. (NCI04)/NCI-GLOSS Definition: An anticancer drug that is a type of antiandrogen.
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Synonyms & Abbreviations |
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
4'-Nitro-3'-trifluoromethylisobutyranilide
Alpha,alpha,alpha-trifluoro-2-methy-4'-nitro-m-propionotoluidide
Apimid
Cebatrol
Chimax
Cytomid
Drogenil
Euflex
Eulexin
Eulexine
Flucinom
Flucinome
Flugerel
Fluken
Flulem
FLUT
Fluta-Gry
Flutabene
Flutacan
Flutamex
Flutamide
flutamide
FLUTAMIDE
Flutamin
Flutan
Flutaplex
Fugerel
Grisetin
Niftolide
Oncosal
Profamid
Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-
Prostacur
Prostadirex
Prostica
Prostogenat
Sch 13521
SCH 13521
Tafenil
Tecnoflut
Testotard
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ReferenceCode |
NCI Thesaurus Code:C509
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ReferenceURL |
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C509
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PMID |
NA
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