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Definition |
A derivative of dipyridamole that is a phosphodiesterase inhibitor, with potential antiplatelet activity. Mopidamol inhibits the hydrolysis of cyclic nucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), by cyclic nucleotide phosphodiesterases; thus, cAMP- and cGMP-dependent processes are potentiated. This leads to the induction of prostacyclin synthesis, the inhibition of thromboxane B2 synthesis and prevention of platelet activation and aggregation.
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Synonyms & Abbreviations |
2,2',2",2"'-[(4-Piperidinopyrimido[5,4-d-]pyrimidine-2,6-diyl)dinitrilo]tetraethanol
2,2',2",2"'-[[4-(1-Piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol
2,6-Bis(diethanolamino)-4-piperidino-pyrimido[5,4-d]pyrimidine
MOPIDAMOL
Mopidamol
RA-233
Rapenton
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