Prostate Cancer Ontology
Center for Systems Biology, Sichuan University West China Hospital, Sichuan China
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折叠 Prostate cancerProstate cancer
折叠 Epidemiological aspects of prostate cancerEpidemiological aspects of prostate cancer
展开 Basic information of patientBasic information of patient
展开 Personal medical historyPersonal medical history
折叠 Genetic and epigenetic of prostate cancerGenetic and epigenetic of prostate cancer
展开 Lifestyles of prostate cancerLifestyles of prostate cancer
展开 Diagnostic aspects of prostate cancerDiagnostic aspects of prostate cancer
展开 Therapeutic aspects of prostate cancerTherapeutic aspects of prostate cancer
CD82
Preferred Name CD82 CD82 molecule
Definition This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms & Abbreviations R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27
ReferenceCode Location: 11p11.2; Sequence: Chromosome: 11; NC_000011.10 (44565591..44620363)
ReferenceURL https://www.ncbi.nlm.nih.gov/gtr/genes/3732/
PMID NA
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