Prostate Cancer Ontology
Center for Systems Biology, Sichuan University West China Hospital, Sichuan China
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折叠 前列腺癌前列腺癌
折叠 前列腺癌流行病学前列腺癌流行病学
展开 患者基本信息患者基本信息
展开 个人病史个人病史
展开 遗传和表观遗传遗传和表观遗传
折叠 前列腺癌的生活方式前列腺癌的生活方式
展开 个人背景特征个人背景特征
展开 行为习惯行为习惯
体力活动
展开 环境环境
展开 矿物质矿物质
展开 维他命维他命
折叠 药物或手术药物或手术
展开 疾病疾病
展开 社会因素社会因素
展开 食物食物
展开 生理生化生理生化
展开 添加剂添加剂
展开 不清楚的分类不清楚的分类
展开 前列腺癌的诊断前列腺癌的诊断
展开 前列腺癌的治疗前列腺癌的治疗
华法林
Preferred Name Warfarin
Definition A synthetic anticoagulant. Warfarin inhibits the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors, which include Factors II, VII, IX and X, and the anticoagulant proteins C and S. This inhibition results in a sequential depression of Factors VII, IX, X and II activities. Vitamin K is an essential cofactor for the post ribosomal synthesis of the vitamin K dependent clotting factors. The vitamin promotes the biosynthesis of gamma-carboxyglutamic acid residues in these proteins which are essential for biological activity.
NCI-GLOSS Definition: A drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners).
Synonyms & Abbreviations 1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
3-(.alpha.-Acetonylbenzyl)-4-hydroxycoumarin
3-(.alpha.-Phenyl-.beta.-acetylethyl)-4-hydroxycoumarin
3-(Alpha-acetonylbenzyl)-4-hydroxycoumarin
3-Alpha-phenyl-beta-acetylethyl-4-hydroxycoumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
Athrombin-K
Co-Rax
Compound 42
Rodex
WARF Compound 42
WARF compound 42
Warfarin
warfarin
WARFARIN
ReferenceCode NCI Thesaurus Code:C945
ReferenceURL https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C945
PMID NA
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