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Preferred Name |
HMG-CoA Reductase Inhibitor
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Definition |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels.
NCI-GLOSS Definition: Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer.
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Synonyms & Abbreviations |
HMG-CoA reductase inhibitor
HMG-CoA Reductase Inhibitor
Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors
hydroxymethylglutaryl-coenzyme A reductase inhibitor
statin
Statin
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ReferenceCode |
NCI Thesaurus Code:C1655
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ReferenceURL |
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C1655
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PMID |
NA
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