Preferred Name	Metformin
Definition	Definition: An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys. NCI-GLOSS Definition: The active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body's use of the glucose. Metformin is a type of antidiabetic agent.
Synonyms & Abbreviations	1,1-Dimethylbiguanide Metformin metformin METFORMIN N,N-Dimethylimidodicarbonimidic Diamide
ReferenceCode	NCI Thesaurus Code:C61612
ReferenceURL	https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C61612
PMID	NA